All cells from human liver dataset

Macrophages

Ontology Term: macrophageCL:0000235
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: mononuclear phagocyteCL:0000113
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: NDST3, CD5L, LILRB5, SDC3, FOLR2, C1QC, C1QB, CTD-2337J16.1, SIGLEC1, C1QA
Canonical Marker Genes: CSF1R, MAFB
Negative Marker Genes Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.: —
Rationale: Marker genes are top 10 DEGs for this population compared with rest of UMAP (from Table S1 in publication). As most of the population are Kupffer cells (KCs), KC specific genes largely define the population however smaller populations of macrophages are also present. Refer to myeloid cell UMAP for more granularity.

Set of Labels Description: Annotation of cells in dataset based on prior knowledge.
Annotation Method: manual