Achilles tendon atlas - muscle cells 12

Adipocytes

Ontology Term: adipocyteCL:0000136
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: Fat cell
Category Class of which the cell type is a subclass.: connective tissue cellCL:0002320
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: PLIN1, LPL, GPAM, AQP7, ADIPOQ
Canonical Marker Genes: PLIN1, PLIN4, ADIPOQ, GRAM, AQP7
Negative Marker Genes Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.: —
Rationale: This cell was annotated manually using canonical markers in the field (PLIN1, ADIPOQ, AQP7). We noticed PLIN1, PDE3B running differential expression.
Rationale DOI: https://doi.org/10.1113/JP287812 10.1096/fj.202300601RRR

Set of Labels Description: Lineage annotations were determined by Louvain clustering at resolution 0.1. Each lineage (fibroblast, muscle, immune, stromal) was then subsetted and reclustered. Final annotation resolution was chosen according to expression of biological markers; smaller clusters were combined were appropriate
Annotation Method: manual