Human liver cell atlas - myeloid cells

Main

Cell Metadata

Summary

Innate immune cells including macrophages and dendritic cells, key in tissue homeostasis and immune surveillance. These are version 1 cell type labels and may be subject to change.

Metadata

Dataset Type: Single. The file includes a single dataset whereby “dataset” means a single library or a set of technical replicates that can be combined without having to worry about the associated batch effect.
Total Cells: 65,575
organism: Homo sapiens
disease: normal
assay: 10x 3' v3 (43,133 cells)10x 3' v2 (20,150 cells)10x 5' v1 (2,292 cells)
tissue: liver (35,810 cells)caudate lobe of liver (15,563 cells)right lobe of liver (7,731 cells)left lobe of liver (6,471 cells)

Cell Labels

Summary

Innate immune cells including macrophages and dendritic cells, key in tissue homeostasis and immune surveillance. These are version 1 cell type labels and may be subject to change.

Metadata

Dataset Type: Single. The file includes a single dataset whereby “dataset” means a single library or a set of technical replicates that can be combined without having to worry about the associated batch effect.
Total Cells: 65,575
organism: Homo sapiens
disease: normal
assay: 10x 3' v3 (43,133 cells)10x 3' v2 (20,150 cells)10x 5' v1 (2,292 cells)
tissue: liver (35,810 cells)caudate lobe of liver (15,563 cells)right lobe of liver (7,731 cells)left lobe of liver (6,471 cells)

Cell Labels

author_cell_type

Description

HLiCA classifies cells into six lineages and 48 distinct cell types, 18 more than previous studies. Rigorous benchmarking ensured robust integration across technical and biological variables. Expanded annotations allowed identification of previously undetected liver cell types. As the largest human liver cell atlas, HLiCA serves as a genetically diverse, well-annotated reference.

Annotation Method

both